Dexamethasone or hydrocortisone would suppress the local inflammation caused by tissue trauma that occurs during the treatment process. Hyaluronidase is an enzyme responsible for degrading hyaluronic […]
Depending on the reaction type of the reaction severity, the dose should be decreased and patient status is to be monitored, as mentioned, the regular dose is 3.6mg per kg, If this dose induced some reaction/toxicity, next dose should be 3mg per kg, and the following dose is 2.4mg per kg if another reaction took place with the first dose adjustment, however if the reaction still not controlled with the second dose reduction, the treatment should be discontinued and alternative therapy should be pursued.
Exposure can occur at any point dealing with the hazardous materials, starting from receiving the items from the vendors to the pharmacy stores all the way to the patient administration / infusion time. Any personnel dealing with hazardous drugs, through transportation, clean room preparation, patient dosage administration or even waste disposal may be at risk.