How to Prepare Diovan Suspension?

How to Prepare Diovan Suspension?

The following preparation will result in an extemporaneous preparation of Valsartan 10 mg/mL in SyrSpend SF PH4.

Valsartan, an angiotensin II receptor antagonist, is used to treat hypertension, heart failure, and left ventricular dysfunction in adults and children aged 6 and older. Valsartan is occasionally used alongside other antihypertensive drugs.

Stability

This preparation has a shelf life of up to 90 days when packed in low-actinic, light-resistant prescription containers and kept at room or refrigerator temperature.

Valsartan black box warning

Direct renin-angiotensin system inhibitors may harm or kill a growing fetus. If you’re pregnant, stop taking Valsartan right away.

Notes on how to prepare Diovan suspension?

• Oral suspension made from tablets is more bioavailable than tablets. Reevaluate dosage when transitioning to oral suspension.

• Oral dose forms (tablets and compounded suspensions) are not mg:mg bioequivalent. Because oral suspension has a greater bioavailability than tablets, patients may need a larger dose when switching from oral suspension to tablets.