27 MCQs Added – Adverse Drug Reactions

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27 questions added to the Adverse drug reactions MCQs Page. 

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Page 1 of 12

1. A baby swallowed the contents of a 15g tube of nystatin. What should you do to remedy the over dosage?

Call an ambulance immediately

Rush the child to emergency services

Nothing as the dose is too low dose for the child to get any serious side effects

Perform an immediate stomach lavage by giving the child lots of fluid

Administer activated charcoal

2. A child has ingested an unknown substance and has evidence of respiratory depression. This symptom is usually found with poisoning due to:

amphetamines

kerosene

atropine

opioids

mushrooms

Page 2 of 12

3. A doctor and nurse start frantically looking for naloxone for a female patient is suspected of overdosing of IV narcotics. What basic principle in the treatment of poisoning are they overlooking?

Electrolytes

Syrup of ipecac

Blood analysis

Gastric lavage

Control of vital functions

4. A patient complains of headache and his blood pressure is 120/80. His medications include hydrochlorothiazide and hydralazine. Which of the following would seem most likely?

The headaches are related to hydralazine-induced agranulocytosis

The headaches are secondary to thiazide-induced hypokalemia

The headaches are secondary to hydralazine therapy

The headaches are caused by an temporary increased blood pressure

The headaches are probably unrelated to drug therapy

Page 3 of 12

5. A woman phoned you whilst running a busy afternoon clinic. She told you that her husband has swallowed 30 tablets of acetaminophen/paracetamol 325mg. What is the proper advice?

He will be all right, he should not worry and this not a serious concern

Call drug information center for help

Induce emesis-using ipecac

Call the poison center to ask for advice

Refer him to the emergency department

6. Acetaminophen (Tylenol) overdose is treated with:

naloxone

N-acetylcysteine

enteric charcoal

all of these options

IV fluids

Page 4 of 12

7. Adverse effect(s) of laxatives:

Dehydration

Spastic colitis with stimulant laxatives

Gastrointestinal obstruction with bulk forming agents

All of these options

Electrolyte disturbances (hypernatremia, hypokalemia)

8. Adverse effects of beta-2 adrenergic bronchodilators include all of the following EXCEPT:

lethargy

nervousness

headache

headache

tachycardia

Page 5 of 12

9. Antidote for amitriptyline (Elavil) overdose is:

naloxone

N acetylcysteine

physostigmine

physostigmine

atropine

10. Antidote for chlorpromazine overdose is:

naloxone

benztropine

N acetylcysteine

ethanol

physostigmine

Page 6 of 12

11. Blood tests are carried out on patients who take carbimazole, which one below is a FALSE statement?

This is so that the clinician can monitor thyroid levels

This is so that the clinician can monitor for agranular cytosis

This is so that the clinician can monitor for ALT

This is so that the clinician can monitor for anaemia

This is so that the clinician can monitor for hyoglyacaemia

12. Following are characteristics of toxic shock syndrome, EXCEPT:

diffuse macular rash

fever/headache

myalgia/oliguria

increased SGOT/SGPT levels

person to person transmission

Page 7 of 12

13. Grey baby syndrome occurs with which of the following drugs?

Doxycycline

Penicillin

Clarithromycin

Chloramphenicol

14. Nitroglycerin is used for the treatment of angina. A specific concern related to the long term use of this drug is which of the following?

Arthritic pain

Development of A-V heart block when given with hydralazine

Development of profound hypertension when given with sildenafil (Viagra)

Down regulation of receptor sites

Tolerance developing requiring larger doses

Page 8 of 12

15. Opiate intoxication is characterized by which of the following?

All of these options

Increased respiratory rate

Hypotension

Miosis

Bradycardia

16. Reversible Oligospermia is assoicated with which of the following drugs?

Methotrexate

Sulfasalazine

Spironolactone

Cimetidine

Hydrocortisone

Page 9 of 12

17. Some asthmatic patients exhibit aspirin sensitivity (and sensitivity to other NSAIDS). Daily administration of aspirin causes desensitization not only to aspirin also to other NSAIDS. This phenomenon is:

Nocebo

Cross-tolerance

Efficacy

The placebo effect

Potency

18. Which of the following are Type IV hypersensitivity reactions?

Chrons disease

Asthma

Chrons disease and Rhematioid arthritis

Rhematioid arthritis

Asthma and Rhematioid arthritis

Page 10 of 12

19. Which of the following counselling points would NOT be appropriate when talking to a patient about their azathioprine tablets?

You will need regular blood tests while taking this medication

You should avoid coming into contact with anyone with chicken pox

You should inform you doctor if you develop an unexplained rash

You should inform your doctor if you develop an unexplained sore throat

You may feel drowsy with this medication and if affected you should avoid driving or using machinery.

20. Which of the following drug should not be taken on empty stomach?

Cloxacillin

All of these options

Rifampicin

Cefuroxime Axetil

Sucralfate

Page 11 of 12

21. Which of the following is the antidote for the toxin Lead?

Dialysis

Nitrite

Naloxone

CaEDTA

22. Which of the following is the main danger caused by acetaminophen (Paracetamol, Tylenol) overdose?

None of these options

Cardiac failure

Hepatic failure

Renal failure

Brain damage

Page 12 of 12

23. Which one of the following drugs is least likely to cause drug induced blood dyscrasia or agranulocytosis?

Clozapine

Methotrexate

Aminosalicylates such as sulfasalazine

Phenytoin

Carbimazole

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