Dopaminergic Post

how dopamine works?

Dopamine works on both adrenergic and dopaminergic receptors, starting from lower dosing, as you go up effects on adrenergic receptors starts to predominate.

LOWER DOSES
Mainly dopaminergic, working on renal and mesenteric vasodilation

HIGHER DOSES
Same as lower doses, but with beta1-adrenergic action and produce cardiac stimulation; larger doses stimulate alpha receptors

DOSE (ADULT)

ACTION

Low dose
1 to 5 mcg/kg/minute

increased renal blood flow and urine output

Intermediate dose
5 to 10 mcg/kg/minute

same as lower dosing + increased heart rate, cardiac output and contractility

High dose
10 mcg/kg/minute

same as intermediate dosing + vasoconstriction thus increased blood pressure

Obaid

Pharmacist, CPHQ, CHQO, Quality Coordinator, Chemotherapy Preparation incharge. Graduated pharmacy school in 2009 I stood with my classmates as we recited the “Oath of a Pharmacist” in. There is one particular vow that stood out to me as we recited the Oath and I embrace this vow, “I will apply my knowledge, experience, and skills to the best of my ability to assure optimal outcomes for my patients.” I love being a pharmacist because it allows me to use my knowledge, abilities, and talents to improve patient outcomes in the community hospital in which I am employed as the pharmacy clinical coordinator.

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