Angiotensin-II Receptor Antagonist
July 3, 2017Nitrates, Calcium Channel Blockers and Other Antianginal Drugs
July 3, 2017Terazosin:
Indications: indicated for the treatment of symptomatic benign prostatic hyperplasia (BPH). also indicated for the treatment of hypertension alone or in combination with other antihypertensive agents such as diuretics or betaadrenergic blocking agents.
Contraindications: contraindicated in patient’s known to be hypersensitive to terazosin hydrochloride.
Dose and Administration: Benign Prostatic Hyperplasia: 1 mg at bedtime is the starting dose The dose should be increased in a stepwise fashion to 2 mg, 5 mg, or 10 mg once daily to achieve the desired improvement of symptoms and/or flow rates. Hypertension: The usual recommended dose range is 1 mg to 5 mg administered once a day; however, some patients may benefit from doses as high as 20 mg per day.
Doxazosin:
Indications: treatment of both the urinary outflow obstruction and obstructive and irritative symptoms associated with BPH. also indicated for the treatment of hypertension alone or in combination with diuretics, beta-adrenergic blocking agents, calcium channel blockers or angiotensin-converting enzyme inhibitors.
Contraindications: contraindicated in patients with a known sensitivity to quinazolines.
Dose and Administration: Benign Prostatic Hyperplasia 1–8 mg once daily. Hypertension 1–16 mg once daily.
Alfuzosin:
Indications: indicated for the treatment of signs and symptoms of benign prostatic hyperplasia. It is not indicated for the treatment of hypertension. Contraindications: contraindicated for use in patients with moderate or severe hepatic impairment, contraindicated for use with potent CYP3A4 inhibitors such as ketoconazole, itraconazole, and ritonavir.
Dose and Administration: The recommended dosage is one 10 mg once daily.
