Winner OneTouch Verio was chosen by 274 out of 353 HCWJuly 30, 2021
FMEA – Failure Mode and Effects AnalysisJuly 31, 2021
Question number one
When treating patients with Helicobacter pylori infection who have previously been exposed to macrolides, which treatment approach does the American College of Gastroenterology (ACG) recommend?
- Clarithromycin-based triple treatment is recommended.
- A proton pump inhibitor (PPI) and amoxicillin are used to treat the infection.
- Bismuth quadruple therapy is a kind of treatment.
- Amoxicillin is used in a high-dose dual regimen.
Question number two
The presence of significant levels of antibiotic resistance, along with treatment failure, has rendered conventional first-line therapy for the treatment of Helicobacter pylori infections unsuitable in many areas.
Question number three
The patients in a recent Phase 3 trial evaluating three different first-line treatments for H. pylori infection were randomized to one of three treatments: vonoprazan with amoxicillin (dual P-CAB), vonoprazan with amoxicillin and clarithromycin (triple P-CAB), or lansoprazole with amoxicillin and clarithromycin (triple P-CAB) (triple lansoprazole). As opposed to lansoprazole, which of the following statements better characterizes the P-CAB regimens:
- The effectiveness of dual P-CAB treatment was shown to be inferior to that of triple P-CAB therapy and triple lansoprazole therapy.
- The use of triple lansoprazole was shown to be better to the use of dual P-CAB treatment.
- Each of the P-CAB regimens was shown to be non-inferior to triple lansoprazole treatment.
- The use of triple lansoprazole was shown to be superior to both P-CAB regimens.