Generic Name : Trimethoprim Indication : Treatment of urinary tract infections due to susceptible pathogens Dosage Form : Suspension Strength : 10mg/mL Stability : 6 weeks at 25°C, 3 months at 4°C Storage : Refrigerate (preferable) or at room temperature and protect from light
How to prepare TRIMETHOPRIM SUSPENSION 10MG/ML: 1. Prepare 100mL of a mixture of equal parts methylcellulose 1% and syrup. 2. Crush the trimethoprim tablets and then slowly add the base whilst mixing. 3. Add more vehicle to the paste until liquid is formed and transfer the liquid into a container. 4. Use additional vehicle to rinse the remaining drug from the mortar and pour into the container. 5. Make up to final volume with vehicle. 6. Shake well and label.
NOTES: 1. A suspending base of methylcellulose 1-2% without syrup can be used if preferred. 2. Keep in an amber plastic bottle.