ACETAZOLAMIDE SUSPENSION 25MG/ML

Viewing 0 reply threads
  • Author
    Posts
    • #48726
      Alchemist
      Participant

      ACETAZOLAMIDE SUSPENSION 25MG/ML
      Generic Name: Acetazolamide
      Indication: Reduction of intra-ocular pressure in open-angle glaucoma, Secondary glaucoma and peri-operatively in angle-closure glaucoma
      Dosage Form: Suspension
      Strength: 25mg/mL
      Stability: 60 days
      Storage: Refrigerate (preferable) or at room temperature

      Ingredients:
      Acetazolamide 250mg 12 tablets
      Vehicle qs 120mL

      VEHICLE OF CHOICE:
      • Ora-Sweet®: Ora-Plus® (1:1) or
      • Ora-Sweet SF®: Ora-Plus®(1:1) or
      • Ora-Blend SF® or
      • Cherry syrup or
      • Equivalent vehicle to Ora-Sweet®: Ora-Plus® (1:1)

      How to prepare ACETAZOLAMIDE SUSPENSION 25MG/ML:
      1. Crush tablets in a mortar to fine powder.
      2. Levigate the powder with small amount of vehicle until smooth paste is formed.
      3. Add more vehicle to the paste until liquid is formed and transfer the liquid into a container.
      4. Use additional vehicle to rinse the remaining drug from the mortar and pour into the container.
      5. Make up to final volume with vehicle.
      6. Shake well and label.

      REFERENCES:
      1. Allen LV, Erickson MA.(1996) Stability of acetazolamide allopurinol, azathioprine, clonazepam, and flucytosine in extemporaneously compounded oral liquids. Am J Health Sys Pharm. 53:1944.

Viewing 0 reply threads

You must be logged in to reply to this topic.

gdpr-image
This website uses cookies to improve your experience. By using this website you agree to our Cookie Policy.
Read more