Ruth Myers

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  • in reply to: Maximum daily dose of Ondansetron #49130

    Ruth Myers
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    As per the reference(Lexicomp Online), yes you can up to 48 mg per day divided into 3 doses, but I think for pedia patient you will not reach this dose unless obese patient more than 100 Kg.

    Note: Single IV doses >16 mg are no longer recommended by the manufacturer due to the potential for QT prolongation

    To avoid this risk, you may consider addition of another group of treatment such Substance P/Neurokinin 1 Receptor Antagonists per MASCC guidelines, antiemetic regimen also includes Dexamethasone and aprepitant or fosaprepitant.

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Ruth Myers
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