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June 7, 2017 at 5:20 pm
#49130
Ruth Myers
Participant
As per the reference(Lexicomp Online), yes you can up to 48 mg per day divided into 3 doses, but I think for pedia patient you will not reach this dose unless obese patient more than 100 Kg.
Note: Single IV doses >16 mg are no longer recommended by the manufacturer due to the potential for QT prolongation
To avoid this risk, you may consider addition of another group of treatment such Substance P/Neurokinin 1 Receptor Antagonists per MASCC guidelines, antiemetic regimen also includes Dexamethasone and aprepitant or fosaprepitant.
