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To avoid relapses, you should consult your doctor to determine the best antibiotic. Infections with C. diff can be life-threatening and even fatal.
Firvanq®
FIRVANQ® is a glycopeptide antibacterial indicated in adults and pediatric patients less than 18 years of age for the treatment of:
Clostridium difficile-associated diarrhea. Enterocolitis caused by Staphylococcus aureus (including methicillin-resistant strains).
Clostridium Diff.
Orally administered vancomycin hydrochloride is not effective for treatment of other types of infections.
C difficile colitis results from a disruption of the normal bacterial flora of the colon, colonization with C difficile, and release of toxins that cause mucosal inflammation, mucosal damage, and diarrhea.
FIRVANQ® uses
Clostridium difficile-associated diarrhea and Enterocolitis caused by Staphylococcus aureus (including methicillin-resistant strains).
How long can oral vancomycin be left unrefrigerated
- Store the FIRVANQ kit at refrigerated conditions, 2°C to 8°C (36°F to 46°F).
- Do not freeze. Keep container tightly closed. Protect from light.
- Store the reconstituted solution of FIRVANQ at refrigerated conditions, 2°C to 8°C (36°F to 46°F) when not in use.
- Discard the reconstituted solution of FIRVANQ after 14 days, or if it appears hazy or contains particulates.
How to Reconstite FIRVANQ (vancomycin hydrochloride for oral solution?
FIRVANQ® Dosing
FIRVANQ® is a glycopeptide antibacterial that is indicated for the treatment of enterocolitis caused by Staphylococcus aureus and Clostridium difficile. This drug is taken orally as 500 mg to 2 g orally in 3 or 4 divided doses for 7 to 10 days. The total daily dosage should not exceed 2 g.
FIRVANQ® FAQ
1How does FIRVANQ® works?
FIRVANQ® is an oral solution of vancomycin hydrochloride, which is an important ingredient in Clostridium-difficile treatment. It acts on bacterial cell walls to alter their permeability and kill bacteria. It is the first drug to contain this ingredient. As a glycopeptide antibiotic, vancomycin is a class A antibiotic and affects the permeability of bacterial cell membranes. It is used to treat enterocolitis caused by Staphylococcus aureus, and to treat diarrhea associated with Clostridium difficile.
So, basically Vancomycin Inhibits bacterial cell wall synthesis by blocking glycopeptide polymerization through binding tightly to D-alanyl-D-alanine portion of cell wall precursor.
2Is FIRVANQ® available as tablet or capsule?
FIRVANQ® comes in 25 mg/mL or 50 mg/mL kits.
Each kit contains a bottle of vancomycin hydrochloride USP powder for oral solution and a bottle of grape‑flavored diluent for simple reconstitution.
3Can you take FIRVANQ® to treat Clostridium difficile without doctor order?
In order to properly diagnose FIRVANQ® for C. diff infection, a person should undergo a stool culture and blood test. These tests will determine whether the patient is harboring the bacteria that causes the disease. A stool sample may reveal the strain of bacteria that caused the infection.
4Can FIRVANQ® Cause Clostridium Difficile Colitis?
However, the drug can cause a recurrence. Some people with C. diff. can still use FIRVANQ® to treat the infection. The medication is effective for C. diff. Infections caused by staph or c. difficile occur in the colon. Infected individuals with colitis may need a higher dose of the drug.
