CYCLOPHOSPHAMIDE PROTOCOL FOR RPGN

ONE HOUR PRIOR THE INFUSION HYDRATES WITH 500CC NORMAL SALINE FOR ONE HOUR.
HALF AN HOUR PRIOR THE INFUSION GIVE :-
ONDANSETRON 8MG TAB (ONE TAB.) STAT
MESNA(UROMETEXAN) 200MG IN 100CC NORMAL SALINE IV OVER 30 MIN.
CYCLOPHOSPHAMIDE(ENDOXAN) INFUSION AS FOLLOW:
1000MG + MESNA 400 MG IN 500CC NORMAL SALINE TO BE INFUSED OVER ONE HOUR.

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