Radiology Preparations

Radiology Preparations

IOHEXOL:

Indications: It is an X-ray contrast medium for use in adults and children for cardioangiography, arteriography, urography, phlebography and CT-enhancement. Lumbar, thoracic, cervical myelography and computed tomography of the basal cisterns, following subarachnoid injection. It is also indicated for arthrography, endoscopic retrograde pancreatography (ERP), endoscopic retrograde cholangiopancreatography (ERCP), herniography, hysterosalpingography.

Contraindications: Manifest thyrotoxicosis. History of serious reaction to Iohexol.

Dose and Administration: The dosage varies depending on the type of examination, age, weight, cardiac output and general condition of the patient and the technique used. Usually the same iodine concentration and volume is used as with other iodinated X-ray contrast media in current use. Adequate hydration should be assured before and after administration as for other contrast media.

IOBITRIDOL:

Indications: intravenous urography, computed tomography, intravenous digital subtraction angiography, arteriography, and angiocardiography.

Contraindications: Manifest thyrotoxicosis. History of serious reaction to Iohexol.

Dose and Administration: The doses must be adapted to the examination and the regions to be opacified, as well as to the body weight and renal function.

Source: Obaid

GADODIAMIDE:

Indications: It is a contrast medium for cranial and spinal magnetic resonance imaging (MRI). It is also indicated for whole body MRI including head and neck region, thoracic space including the heart, extremities, abdomen and pelvis (prostate and bladder), female breast, abdomen (pancreas and liver), retroperitoneal space (kidney), musculosceletal system and vessels (angiography) by intravenous administration. Omniscan facilitates visualisation of abnormal structures or lesions and helps in the differentiation between healthy and pathological tissue.

Contraindications: Hypersensitivity to the active substance gadodiamide or to any of the excipients. Gadodiamide is contraindicated in patients with severe renal impairment (GFR <30 ml/min/1.73m2), and those who have had or are undergoing liver transplantation.

Dose and Administration: The recommended dosage to adults and children is 0.2-ml/kg body weight (b.w.) (0.1 mmol/kg b.w.) up to 100 kg. Above 100 kg body weight 20 ml is usually sufficient. When brain metastases are suspected, a dosage of 0.6 ml/kg b.w. (0.3 mmol/kg b.w.) can be administered to adults up to 100 kg. Above 100 kg bodyweight a total of 60 ml is usually sufficient. The dose of 0.6 ml/kg can be administered as a single injection. Alternatively a second bolus injection of 0.4 ml/kg b.w. (0.2 mmol/kg b.w.) may be administered within 20 minutes of the first injection of 0.2 ml/kg b.w. (0.1mmol/kg b.w.).

GADOTERIC ACID:

Indications: Magnetic Resonance Imaging for: cerebral and spinal disease; diseases of the vertebral column; other whole-body pathologies (including angiography).

Contraindications: Hypersensitivity to the active substance or to any of the excipients.

Dose and Administration: The recommended dose is 0.1 mmol/kg, i.e. 0.2 mL/kg in adults, children and infants.
In angiography, depending on the results of the examination being performed, a second injection may be administered during the same session if necessary. In some exceptional cases, as in the confirmation of isolated metastasis or the detection of leptomeningeal tumours, a second injection of 0.2 mmol/kg can be administered.

The product must be administered by strict intravenous injection.

 

 

image sources

  • IOBITRIDOL: Obaid

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