Drugs for dementia

RIVASTIGMINE:

Indications: mild to moderate dementia in Alzheimer’s disease or in Parkinson’s disease.

Contraindications: breast-feeding.

Dose and Administration: Initially 1.5 mg twice daily, increased in steps of 1.5 mg twice daily at intervals of at least 2 weeks according to response and tolerance; usual range 3–6 mg twice daily; max. 6 mg twice daily.

MEMANTINE HYDROCHLORIDE:

Indications: moderate to severe dementia in Alzheimer’s disease.

Contraindications: breast-feeding.

Dose and Administration: Initially 5 mg in the morning, increased in steps of 5 mg at weekly intervals, up to max. 10 mg twice daily; doses over 5 mg given in 2 divided doses.

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